How long does it take to see results?

Clinical studies suggest that Berberine+ can achieve effects after 2-3 months of daily use.

Do I need to take Berberine+ with food?

The best time to take berberine is immediately before or during a meal. If it's possible to take Berberine+ before your largest meal of the day, research suggests that may be ideal for maximizing its effects.

Are there dietary sources of curcumin?

Yes, curcumin is commonly consumed in turmeric and in curries. The average American diet contains very little curcumin (approximately 3mg), while elsewhere in the world the average diet may contain closer to 60-100mg daily.

Do you ship outside of the United States?

Innerbody Labs ships to countries across the globe, and our reach is expanding. Currently, we ship internationally to Australia, New Zealand, Canada, the United Kingdom, and Ireland.

NEW

NEW

Berberine+

4.7

Rated 4.7 out of 5 stars

4.7 Stars (19 Reviews)

A smarter combination for metabolic health support

Phytosomal berberine and curcumin combine in this precision formula to deliver the clinically studied metabolic support without GI upset.*

Cardiovascular Health*
Blood Glucose*
Healthy Fat Metabolism*
PCOS*

Vegetarian Friendly
Gluten-Free
cGMP-Certified
Non-GMO
Dairy-Free
Lab-Tested

Quantity: 3-Month Supply

6-Month Supply
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1-Month Supply

BLACK FRIDAY: UP TO 55% OFF +
FREE FOCUS SUPPORT ON ORDERS $125+

Black Friday pricing as marked and valid on first subscription order only. Standard bundle savings apply to renewals. Cannot be combined with other discounts. Must add one bottle of Focus Support to a qualifying $125+ cart.

1 Month Supply

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Astaxanthin+

Helps Protect Against Oxidative Stress*
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GMP-Certified Facility

Made in the USA with globally sourced ingredients

Third-Party Testing

Made in FDA
Registered Facility

Heavy Metal / Contaminant Tested

Science-backed formulas

Benefits

Healthy blood glucose

Multiple studies confirm berberine’s ability to support healthy blood glucose levels. *

Cardiovascular health

Research has shown Berberine's potential in supporting healthy blood pressure and cardiovascular health.

Fat metabolism

Lipid metabolism is a hallmark of berberine’s potential, with research indicating disease/treatment territory.

Gentle on the stomach

A branded phytosomal berberine provides more efficacy from a smaller dose and prevents the GI distress that plagues berberine HCl.*

Healthy blood glucose

Multiple studies confirm berberine’s ability to support healthy blood glucose levels. *

Cardiovascular health

Research has shown Berberine's potential in supporting healthy blood pressure and cardiovascular health.

Fat metabolism

Lipid metabolism is a hallmark of berberine’s potential, with research indicating disease/treatment territory.

Gentle on the stomach

A branded phytosomal berberine provides more efficacy from a smaller dose and prevents the GI distress that plagues berberine HCl.*

Every Ingredient Earns Its Place.

Our formulas are built around one principle: every ingredient should have a clear purpose.

We select clinically studied ingredients, use doses aligned with published human research, and combine them thoughtfully to work with your body's natural biology. If an ingredient doesn't meet our standards for evidence, quality, or long-term safety, we leave it out.

The Innerbody Labs Standard

Human-First Evidence

Evidence-based Dosing

Third-Party Tested

Clinically studiedNo proprietary blends

See what we included and why

Berbevis® Berberine Phytosome550 mg

Supports healthy blood pressure, lipid profiles, and blood glucose — without the GI risk*

For the better part of a century, berberine has performed exceptionally well in human studies looking at metabolic health — including research into blood pressure, glucose management, lipid profiles, and more.*

Berbevis® berberine phytosomes deliver more berberine where it’s needed most, allowing you to take a smaller dose and reduce the risk of adverse GI effects associated with traditional berberine HCI. Berbevis® phytosomal berberine boasts a tenfold increase in bioavailability compared to standard berberine HCl, which allows you to experience the clinically proven benefits with minimal side effects.

Meriva® Curcumin Phytosome100 mg

For further support of metabolic health, antioxidant activity, and GI comfort*

Curcumin research dates back about as long as berberine’s, and it shows many of the same benefits, with improvements in metabolic health markers.* We use phytosomal curcumin (Meriva®) for its improved bioavailability, at a 100 mg dose which has been studied to relieve GI discomfort.

Ingredients We Don’t Include

Choosing what not to include is just as important as choosing what goes in. If an ingredient lacks sufficient evidence, raises meaningful safety concerns, or doesn't clearly improve the formulation, we leave it out, regardless of how popular it may be.

Artificial dyes

Titanium dioxide

Proprietary blends

Animal-derived gelatins

Talc

Supported By Clinical Research

In an in vitro pharmacokinetic study, a phytosomal preparation of berberine called Berbevis demonstrated significantly superior absorption compared with traditional berberine hydrochloride, resulting in peak concentrations that were over 3 times higher.

*Petrangolini, G., et al (2021). Development of an innovative berberine food-grade formulation with an ameliorated absorption: In vitro evidence confirmed by healthy human volunteers pharmacokinetic study. Evidence-Based Complementary and Alternative Medicine,2021(1), 7563889. 10.1155/2021/7563889.

In a 2024 clincal study, a total daily dose of 98mg curcumin alongside 400mg berberine significantly improved patients’ IBS severity index and primary IBS symptoms.

*Wade, U., et al (2024). The possible synergistic pharmacological effect of an oral berberine (BBR) And curcumin (CUR) Complementary therapy alleviates symptoms of irritable bowel syndrome (IBS): Results from a real-life, routine clinical practice settings-based study. Nutrients, 16(8), 1204. 10.3390/nu16081204

Peak Berberine Concentration

Total peak concentration (Cmax) 550mg Berbevis (pg/mL)

Total peak concentration (Cmax) 500mg berberine HCl (pg/mL)

Customer Reviews

4.7

Rated 4.7 out of 5 stars

Based on 19 reviews

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19 reviews

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kate
Verified Buyer
I recommend this product
Age 35-44
Gender Female
How long have you been taking this product? 1–3 months
Rated 5 out of 5 stars
4 days ago
so far so good
i've been taking it every day for a couple months and my HDL levels increased in my bloodwork and my triglyceride went down. i've done nothing else aside from walk a little more maybe. i'm going to stick with this.
Was this helpful?
Christina C.
Verified Buyer
I recommend this product
Age 45-54
Gender Female
How long have you been taking this product? Less than 2 weeks
Rated 4 out of 5 stars
5 days ago
I think it’s helping
I believe I do benefit from this supplement.
Was this helpful?
brett m.
Verified Buyer
I recommend this product
Age 45-54
Gender Male
How long have you been taking this product? 2–4 weeks
Rated 5 out of 5 stars
1 week ago
best formula on the market
they get the formula right. it's refreshing when someone's honest with you about not needing more of something.
Was this helpful?

Frequently asked questions

Unfortunately, you can't get meaningful amounts from dietary sources. Edible food items containing berberine are relatively rare (such as barberry fruit) and contain very little compared to the amounts shown in studies to provide benefits. Other natural sources that are richer in berberine (e.g., plant roots) are inedible.

For safety reasons, people who are pregnant or breastfeeding should not take this supplement. Nor should people under age 18. Berberine+ — and berberine supplements in general — may also be unsafe for you if you take certain prescription medications (e.g., blood thinners or blood sugar medications) or have certain underlying health conditions. The effects of berberine are significant, and taking berberine alongside some medications can lead to dangerous, life-threatening situations. You should talk to your doctor first before adding Berberine+ or any other supplement to your routine.

High doses of curcumin (e.g., 1,000mg and higher) can increase risk of GI upset and may cause liver inflammation. Conversely, low doses of curcumin have been shown in studies to reduce GI upset and to protect the liver. That's why Berberine+ includes a helpful, low dose of curcumin at 100mg. Nevertheless, curcumin — like berberine — can inhibit certain liver enzymes, which makes it risky for people on some medications. Talk to your doctor to make sure curcumin is safe for you.

Research suggests that berberine may help achieve modest reductions in weight and belly fat, but not major changes. Its more significant effects in fat metabolism, according to clinical research, involve reduction of triglycerides to support cardiovascular health.

We formulated Berberine+ to be effective and safe for most healthy adults, based on human research. But as with any supplement, it's important to talk to your doctor before adding this to your routine. Berberine+ may affect how certain prescription medications are metabolized and may be inadvisable. Only through discussion with your healthcare practitioner can you arrive properly at a conclusion that the supplement is safe and recommendable for you, based on your underlying health and any medications or supplements you are already taking.